Presented by Dr. Vikas P. Sukhatme on December 8, 2015 at MIT in Cambridge, MA.
Lung cancer is sometimes diagnosed in its early stages yet despite surgery, radiation, and chemotherapy, these tumors often recur systemically and lead to death. Retrospective data show that a pre-operative single dose of an existing therapeutic used off-label tended to increase metastasis-free survival over 10 years by about 15%. If proven, this simple, inexpensive, and non-toxic intervention could save the lives of nearly 5,000 lung cancer patients and half a billion dollars in healthcare costs annually in the US alone. However, with today’s drug development model it will never be adopted as standard of care—with little to gain financially, pharmaceutical companies have little interest in sponsoring the prospective trial necessary to validate the data. GlobalCures, a non-profit medical research organization, exists to fill this gap and its model will be presented.
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